Nintil

Links (90)

2025-08-09 · 00:00 UTC ·1 min read

Brief

Nintil's Links (90) (2025-08-09) is a short curated roundup linking science and industry pieces: it emphasizes new work on cellular memory and argues inflammaging stems from industrial lifestyles/obesity, cites an RCT where psychotherapy reduced chronic pain, and collects essays on AI vs. outsourcing (Steven Byrne), concerns about AI coding tools, and critiques of the SaaS model.

Why it matters

Nintil Links (90) (published 2025-08-09) curates recent research claiming inflammaging is mainly a byproduct of industrialized lifestyles and obesity, and highlights new work on cellular memory and the interpretation of heritability.

Key details

  • The roundup flags an RCT that found psychotherapy reduced chronic pain (testing the claim that much chronic pain is 'in your head'), and collects industry pieces: Steven Byrne on 'AI Against Outsourcing' (vertical integration), critiques of AI coding tools as harmful, and commentary that SaaS underperformed early expectations.
Source evidence

title: Links (90)
contenttype: article
publication: Nintil
published: 2025-08-09T00:00:00+00:00
sourceurl: https://nintil.com/links-90/

word_count: 249

Good post on what the meaning of heritability . Only a crazy person should do any given job A while back I noted that everything sleeps. Now here some recent work on the why. Memory in cells As I noted a while back, inflammaging is not an intrinsic feature of aging; rather it is a byproduct of industrialized lifestyles and most likely just obesity (which increases with age in industrialized countries) On China's shipbuilding industry SSC reviews Steven Byrne's work on AI Against outsourcing , for vertical integration Dwarkesh on the LBJ biographies Facebook's questionable business tactics RCT testing a core woo caim (that a lot of chronic pain is in your head and thus can be treated with psychotherapy), woo succeeds. 50 things Cate Hall knows. Some to disagree with "Ideas are cheap and easy to find; execution is everything" This is very wrong; lots of good ideas go around untried because though some are aware of it, not enough are feeling their truths in their bones. To me there's a big gap between "finding/being aware of an idea" (easy, cheap) and being so convinced to want to go all in into it (hard, the bottleneck). Execution, comparad to that, is easy. The original Flexport pitch Making mercury from gold ? Can goodness compete ? SaaS didn't turn out to be as good of a business model as originally thought. AI coding tools considered harmful I recorded a new podcast I ask Twitter for iconic company culture handbooks